Chemotherapy and Cutaneous Drug Reactions

Over the last two decades, new chemotherapeutic agents have been used for the treatment of cancer with remarkable efficacy. Despite these positive effects, several dermatologic adverse events have emerged such as xerosis, alopecia, papulo-pustular rash, nail damage, trichomegaly, hand–foot syndrome, EMPACT syndrome, and oral mucositis, affecting the quality of life of these patients. The dermatologist plays a critical role in the management of these adverse effects, through pharmacological and dermocosmetological treatment, to cure them and to prevent avoiding the interruption of these therapies for skin toxicity. To better standardize these reactions and their management is an important tool for the dermatologist.